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    2. 目錄多肽

      名稱 Rabbit Anti-ApoER2 Antibody
      編碼 DK-018
      規格 0.1ml/100ug
      價格 inquiry
      中文名 載脂蛋白E2受體抗體
      描述 Cell surface receptor for Reelin (RELN) and apolipoprotein E (apoE)-containing ligands. LRP8 participates in transmitting the extracellular Reelin signal to intracellular signaling processes, by binding to DAB1 on its cytoplasmic tail. Reelin acts via both the VLDL receptor (VLDLR) and LRP8 to regulate DAB1 tyrosine phosphorylation and microtubule function in neurons. LRP8 has er affinity for Reelin than VLDLR. LRP8 is thus a key component of the Reelin pathway which governs neuronal layering of the forebrain during embryonic brain development. Binds the endoplasmic reticulum resident receptor-associated protein (RAP). Binds dimers of beta 2-glycoprotein I and may be involved in the suppression of platelet aggregation in the vasculature. ly expressed in the initial segment of the epididymis, where it affects the functional expression of clusterin and phospholipid hydroperoxide glutathione peroxidase (PHGPx), two proteins required for sperm maturation. May also function as an endocytic receptor.
      抗原類型 abbit polyclonal antibodies
      免疫原 Coupling peptides or recombinant protein
      濃度 1mg/ml
      存儲條件 Store at -20°C.
      亞型 IgG
      成分 Affinity purification,0.01M PBS(pH7.4),1% BSA
      應用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
      性 狀
      儲 存 液

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