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    2. 重組蛋白產品

      名稱 Human VEGFR3 / FLT-4 Protein/重組人 VEGFR3 / FLT-4
      規格 20ug
      編號 CZDB-007
      價格 詢價
      中文名 重組人 VEGFR3 / FLT-4 蛋白
      分子別稱 Chy, Flt-4, VEGFR-3, VEGFR3
      分子種屬 Mouse
      表達標簽 His,S
      表達宿主 E. coli
      濃度 > 95 % as determined by SDS-PAGE
      緩沖液 Lyophilized from sterile PBS, pH 7.4
      存儲條件 -70°C,應避免反復凍融。
      基本描述 Vascular endothelial growth factor receptor 3 (VEGFR3), also known as FLT-4, together with the other two members VEGFR1 (FLT-1) and VEGFR2 (KDR/Flk-1) are receptors for vascular endothelial growth factors (VEGF) and belong to the class III subfamily of receptor tyrosine kinases (RTKs). The VEGFR3 protein is expressed mainly on lymphatic vessels but it is also up-regulated in tumor angiogenesis. Mutations in VEGFR3 have been identified in patients with primary lymphoedema. The VEGF-C/VEGF-D/VEGFR3 signaling pathway may provide a target for antilymphangiogenic therapy in prostate cancer, breast cancer, gastric cancer, lung cancer, non-small cell lung cancer (NSCLC), and so on.

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