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    2. 重組蛋白產品

      名稱 Human TNF-alpha / TNFA Protein/重組人 TNF-alpha /
      規格 20ug
      編號 CZDB-006
      價格 詢價
      中文名 Human TNF-alpha / TNFA Protein/重組人 TNF-alpha /
      分子別稱 TNF-alpha, TNF-a, Cachectin, DIF, TNFA, TNFSF2
      分子種屬 Mouse
      表達標簽 His,S
      表達宿主 E. coli
      濃度 > 95 % as determined by SDS-PAGE
      緩沖液 Lyophilized from sterile PBS, pH 7.4
      存儲條件 -70°C,應避免反復凍融。
      基本描述 Tumor necrosis factor alpha (TNF-alpha), also known as TNF, TNFA or TNFSF2, is the prototypic cytokine of the TNF superfamily, and is a multifunctional molecule involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. Two receptors, TNF-R1 (TNF receptor type 1; CD120a; p55/60) and TNF-R2 (TNF receptor type 2; CD120b; p75/80), bind to TNF-alpha. TNF-alpha protein is produced mainly by macrophages, and large amounts of this cytokine are released in response to lipopolysaccharide, other bacterial products, and Interleukin-1 (IL-1). TNF-alpha is involved in fighting against the tumorigenesis, thus, is regarded as a molecular insight in cancer treatment.

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